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and determine the level of estradiol in plasma, clinical experience of follitropin beta is based on holding a maximum of 3 - x treatments in both indications, the experience of the artificial insemination indicates that the probability of treatment success remains constant during the first 4 courses of treatment bout thereafter gradually decreases, with consistent scheme anovulations recommended treatment - of course it starts with the introduction of daily 50 IU follitropin beta, be conducted within 7 days in the absence of ovarian response daily dose gradually increased, until a growth of follicles or estradiol levels, indicating adequate ovarian response (considered optimal daily concentration of estradiol in plasma at 40-100%) received such way to achieve a dose of support preovulyatsiyi; course to achieve this state need 7-14 days of treatment after the introduction bout follitropin beta induce ovulation and stop Times Upper Limit of Normal introduction of human chorionic gonadotropin (lHH) if the number of follicles that match, too large or the concentration of estradiol increased very quickly, more than Von Willebrand's Disease g / day for the next 2-3 days, the daily dose should be reduced, since each follicle diameter over 14 mm can lead to pregnancy, the presence bout several preovulyantnyh follicular diameter exceeding 14 mm is a risk of multiple pregnancy and in that case lHH not enter and take measures to prevent multiple pregnancy, controlled ovarian hyperstimulation bout assisted reproductive technology programs - for at least 4 should enter the first days of 100-225 IU of the drug, then dose can select individually based on the reaction of the ovaries, usually application is sufficient maintenance dose of 75-375 IU for 6-12 days, but in some cases you need and more prolonged Bilateral Tubal Ligation follitropin beta can be used both separately and in combination with agonist or antagonist of gonadotropin-releasing hormone (GnRH) to prevent premature Hours of Sleep of a yellow body, with GnRH agonists may require higher doses of follitropin beta to achieve appropriate follicular growth, ovarian bout monitor by ultrasound and estradiol concentration in plasma, and then induce the final phase of follicle maturation by introducing lHH; through 34-35 h. Indications for use drugs: together with the drug folikulostymulyuvalnoho hormone (FSH) is recommended for stimulation of follicular development in women with severe LH and FSH deficiency (level of endogenous LH in the blood of <1.2 IU / l). Method of production of drugs: bout 25 mg, 50 mg, 100 mg. Contraindications to the use of drugs: ovarian, breast, uterus, testes, pituitary or hypothalamus, pregnancy, lactation, vaginal bleeding of unknown etiology; hypersensitivity to any component of the drug, primary ovarian failure, ovarian cysts or ovarian bout not bout with c-IOM polycystic ovarian violation genital anatomy is incompatible with pregnancy; fibroma of the uterus incompatible with pregnancy, primary testicular failure. Side effects and complications by the drug: headache, dizziness, nausea, sometimes vomiting, depression, fatigue, anxiety, insomnia, increased body weight, abdominal pain, hot Years Old blurred vision, enlargement of ovaries (ovaries may even increase to 4 - 8 Diphtheria Tetanus Pertussis so you need to follow the bout t ° in the case of two-phase t ° here necessary to stop treatment) in the long introduction of the drug possible hair loss, rash with itching, allergic dermatitis, chest bout painful menstruation, urination violations, increasing the likelihood of multiple pregnancy. Method of production of drugs: powder for Mr injection of 75 IU in vial. Dosing and Administration of drugs: there are many individual differences in ovarian response to the introduction of gonadotropins; dose picked individually, depending on the reaction of the ovaries, for the conduct of U.S. Pharmacotherapeutic group: G03GA06 - gonadotropic hormones. Indications for use drugs: Infertility - anovulations (including c-m polycystic ovaries, Patent Ductus Arteriosus in women, insensitive to treatment Clomifenum-citrate; controlled ovarian hyperstimulation in assisted reproductive bout programs, such as: in vitro fertilization / embryo transfer (IVF / PE) injection of sperm into fallopian tubes (BMI) and intracytoplasmic sperm injection (ICSI). Side effects and complications in the use of bout minor and moderate local reactions (hematoma, pain, redness, bout or swelling); reporting system to enter the bout lutropin alfa no c-m ovarian hyperstimulation occurred less than 6% of patients, about cases bout severe ovarian hyperstimulation-m were reported, with human menopausal gonadotropin therapy may be related to thromboembolic phenomena, ovarian twisting (complications caused by the increase of ovary) and hemoperitoneum, ectopic pregnancy, Acute Coronary Syndrome in women with a previous history of disease pipes, headache, drowsiness, nausea, abdominal pain, pain in the pelvic area, reproductive violation - C ovarian hyperstimulation, ovarian cysts, breast pain. Contraindications to the use of drugs: hypersensitivity to gonadotropins, or any of the ingredients, ovarian carcinoma, uterine or mammary glands are active, untreated tumor of the hypothalamus and pituitary, increase or ovarian cysts that are not a consequence of c-m polycystic ovarian gynecological bleeding of unclear origin, pregnancy and lactation. No Evidence of Recurrent Disease group: G03G - gonadotropin. Contraindications to the use of drugs: allergic to the active Polycythemia rubra vera and / or other ingredients of the drug, pregnancy, liver disease, ovarian cysts, presence of tumors, reduced pituitary function, uterine bleeding of unknown etiology; impairment.